4-(TRIFLUOROMETHOXY)BENZENE-1-CARBONYL CHLORIDE

4-(TRIFLUOROMETHOXY)BENZENE-1-CARBONYL CHLORIDE - Names and Identifiers

Name	4-(Trifluoromethoxy)benzoyl chloride
Synonyms	GVR DOXFFF TIMTEC-BB SBB006550 P-TRIFLUOROMETHOXYBENZOYL CHLORIDE p-(Trifluoromethoxy)benzoyl chloride 4-(TRIFLUOROMETHOXY)BENZOYL CHLORIDE 4-(Trifluoromethoxy)benzoyl chloride Benzoyl chloride,4-(trifluoromethoxy)- [4-(trifluoroMethoxy)phenyl]carbonylchloranuide 4-(TRIFLUOROMETHOXY)BENZENE-1-CARBONYL CHLORIDE
CAS	36823-88-8
EINECS	627-673-9
InChI	InChI=1/C6H15O.BF4/c1-4-7(5-2)6-3;2-1(3,4)5/h4-6H2,1-3H3;/q+1;-1

4-(TRIFLUOROMETHOXY)BENZENE-1-CARBONYL CHLORIDE - Physico-chemical Properties

Molecular Formula	C8H4ClF3O2
Molar Mass	224.56
Density	1.425g/mLat 25°C(lit.)
Boling Point	55-56°C2mm Hg(lit.)
Flash Point	90°F
Appearance	Liquid
Specific Gravity	1.425
Color	Clear colorless to pink
BRN	2723543
Storage Condition	Inert atmosphere,2-8°C
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.472(lit.)
MDL	MFCD00052329

4-(TRIFLUOROMETHOXY)BENZENE-1-CARBONYL CHLORIDE - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R10 - Flammable R34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2920 8/PG 2
WGK Germany	3
FLUKA BRAND F CODES	21
HS Code	29189900
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

4-(TRIFLUOROMETHOXY)BENZENE-1-CARBONYL CHLORIDE - Introduction

4-(Trifluoromethoxy)benzoyl chloride is an organic compound with the chemical formula C8H4ClF3O2. Its nature is as follows:

1. Appearance: It is a colorless to pale yellow oily liquid.
2. Solubility: It can be dissolved in organic solvents, such as ether and dichloromethane, but insoluble in water.
3. odor: a pungent smell.

4-(Trifluoromethoxy)benzoyl chloride is mainly used for the acylation reaction in organic synthesis reaction. It can be used as an acylating agent for the synthesis of other compounds, such as pesticides, pharmaceuticals and important intermediates in organic synthesis.

The method for synthesizing 4-(Trifluoromethoxy)benzoyl chloride is usually obtained by reacting p-benzoyl chloride with trifluoromethanol. Specifically, benzoyl chloride is mixed with trifluoromethyl alcohol under sufficiently dry conditions and heated at low temperature to react to produce 4-(Trifluoromethoxy)benzoyl chloride.

Regarding safety information, 4-(Trifluoromethoxy)benzoyl chloride is an irritating chemical that can cause irritation to the skin, eyes, and respiratory tract. Personal protective equipment, including goggles, gloves and respiratory protection, should be worn during operation. Care should be taken to avoid inhaling its vapors and to ensure that it is used in a well-ventilated area. During storage, it should be kept in a sealed container, away from fire and oxidizing agents. Follow proper safe operating procedures and laboratory regulations for the specific use and handling of this compound.

Last Update：2024-04-09 20:02:46